Pittsburgh Pirates vs. Cincinnati Reds Betting Preview And Odds – September 22, 2021

Posted By Staff on September 22, 2021

The Cincinnati Reds (78-74) are -240 favorites to take Game 3 of their series with the Pittsburgh Pirates (57-94) on Wednesday at 12:35 PM ET. The teams enter the matchup with the series record tied at 1-1, and the underdog Pirates are listed with +195 odds to win the rubber match and take the series victory. Cincinnati is expected to give the ball to Luis Castillo, while Pittsburgh has yet to name a starting pitcher.

Betting Odds

Reds vs Pirates Betting Information
Favorite Favorite Moneyline Underdog Underdog Moneyline Runline Total
Reds -240 Pirates +195 CIN -1.5 8.5

The betting insights and predictions in this article reflect betting data from DraftKings and SportsData.io as of September 22, 2021, 3:00 AM ET.

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Pirates Hitting Leaders

Bryan Reynolds


  • Bryan Reynolds leads Pittsburgh in home runs with 24 and runs batted in with 88.
  • Among qualified hitters in MLB, Reynolds ranks 17th in AVG (.295), sixth in OBP (.376), 19th in SLG (.511), and 17th in hits (155).


Yoshitomo Tsutsugo


  • Yoshitomo Tsutsugo has collected 13 hits this season and has an OBP of .244. He’s slugging .218 on the year.


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