Villanova vs. Penn State Week Betting Odds: Nittany Lions Roar to No. 6 in Polls

Written By Katie Kohler on September 20, 2021 - Last Updated on September 24, 2021
Penn State betting preview

We are…playoff contenders? Maybe. Happy Valley hosted Auburn and a White Out crowd in primetime on Saturday and the Penn State Nittany Lions did not disappoint. They beat Auburn 28-20 to advance to 3-0 on the season. They also covered the 5.5-point spread.

The win moved Penn State from No. 10 to No. 6 in the AP Top 25 Poll. The Nittany Lions National title improved from +6000 during the preseason to +3000.

The Nittany Lions host the Villanova Wildcats on Sept. 25 at 12:00 ET. Early in the week, it was hard to find the matchup listed on sports betting apps. Villanova is an FCS opponent so the game might not be up at most sportsbooks until the end of the week. On Thursday morning, it was on Unibet PA sportsbook and DraftKings with Penn State gvas a 30.5-point favorite and the total points line at 54.5.

Villanova vs. Penn State betting lines, odds and preview

Penn State betting info and stats

  • The Nittany Lions are 3-0 ATS this season.
  • None of Penn State’s three games so far have hit the OVER for total points.
  • Villanova is 3-0. They beat their opponents by a combined score of 136-33.

Ways to bet on college football in Pennsylvania

Pennsylvania is home to thirteen legal and regulated sports betting apps. There, you can bet on Penn State college football in various ways such as:

  • Spread
  • Moneyline
  • Total
  • Live/in-game betting
  • 1st half spread, moneyline, total,
  • Quarters

Player props for college football are not offered at Pennsylvania sportsbooks. So, you won’t see lines for “Sean Clifford over/under passing yards.”

College Football promos at Pennsylvania sportsbooks


  • Bet $1 get $200: New users who place a $1 wager on a college football game or on the NFL, get $200 in free bets.
  • Parlay boost: Get a 33% profit boost on any 3-leg college football parlay.


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Penn State 2021 odds tracker

Penn State over/under win total prior to the start of the season OVER 8.5 (-125)/UNDER 8.5 (+105)

Odds via DraftKings

PreseasonWeek 2
Week 3
Week 4
Week 5
Week 6
Week 7
Week 8
Week 10
National Championsip+6000+5000+5000+3000+3000+2500+7500+20000+50,000
Big Ten Title+900+600+650+500+600+500+1400+50,000
Big Ten East Division +600+500+400
To make playoffsNo (-4000)
Yes (+1300)
No (-1400)
Yes (+700)
No (-3500)
Yes (+1400)
Sean Clifford Heisman+7500+7500+7500+5000+4000+4000+20000

Complete Week 4 College Football Odds at PA Sportsbooks

Lead photo by Barry Reeger/AP

Katie Kohler Avatar
Written by
Katie Kohler

Katie Kohler is a Philadelphia-area based award-winning journalist and Managing Editor at PlayPennsylvania. Katie especially enjoys creating unique content and on-the-ground reporting in PA. She is focused on creating valuable, timely content about casinos and sports betting for readers. Katie has covered the legal Pennsylvania gambling industry for Catena Media since 2019.

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